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Two research teams detail advancements in transplanting pig kidneys to humans, marking key steps on path to clinical trials

Published Sun, 23 Feb 2025 04:10:46 GMT

(CNN) — New advancements in transplanting pig kidneys to humans, detailed by two separate research teams on Wednesday, mark key steps forward in the evolving field of xenotransplantation, the use of non-human tissues or organs to treat medical conditions in humans.Researchers from the University of Alabama at Birmingham Heersink School of Medicine found that transplanted kidneys not only produced urine, they provided the “life-sustaining kidney function” of filtering waste, according to a research letter published in JAMA Surgery.And in a news conference about an ongoing study, a team from New York University Langone Health highlighted the longer-term success of a transplant.Both research teams used genetically modified pig kidneys that were transplanted into recipients experiencing brain death in what is considered pre-clinical human research.Healthy kidneys filter a waste product called creatinine out of the blood. A measure of serum creatinine l...

Late-Week Storms, Nice Weekend

Published Sun, 23 Feb 2025 04:10:46 GMT

More clouds than sun kick off this Thursday morning as temps and dew points run in the 60s, making it feel very similar to what we had stepping out the door yesterday morning. Clouds will occasionally break for some sun today, allowing for a bit better of an afternoon, although it’ll run cooler than average once again. Humidity increases through the day as highs run in the mid 70s. Humidity continues to increase this evening as some scattered showers and storms develop overnight. We’ll track scattered showers and storms tomorrow too as a cold front plows toward the region. With high humidity in place and strong winds aloft, a few of the storms tomorrow could be strong to severe with strong wind gusts and downpours. While the risk is low, it’s not zero, that an isolated brief tornado could spin up as some storms may exhibit rotation. Something to keep an eye on. Once the storms clear late Friday afternoon, the humidity drops off and we dry out for the weekend. Satur...

Former Brazilian military police officer charged with multiple murders arrested in Rye, NH

Published Sun, 23 Feb 2025 04:10:46 GMT

Enforcement and Removal Operations (ERO) Boston recently arrested a former Brazilian military police officer in Rye, New Hampshire, who was convicted of multiple murders and sentenced to more than 200 years in prison for his part in a 2015 Brazilian massacre.Antonio Jose De Abreu Vidal Filho, 29, became the subject of an active Interpol Red Notice issued by the international criminal police organization after he was convicted of 11 murders and sentenced to 275 years and eleven months in prison in June 2023 by a criminal court in the state of Ceara, Brazil. Vidal was convicted, along with three other Brazilian military police officers, of 11 murder charges plus charges of attempted murder and physical and mental torture. The crimes took place in November 2015 during what’s come to be known as the “Curio Massacre” for the name of the neighborhood in the Brazilian city of Fortaleza where they occurred.“The apprehension of this very dangerous foreign fugitive is an outstanding...

Keibert Ruiz hits 3-run shot, Stone Garrett homers twice, Nationals beat Red Sox 6-2

Published Sun, 23 Feb 2025 04:10:46 GMT

WASHINGTON (AP) — Stone Garrett and the Washington Nationals were determined not to waste a superb start by MacKenzie Gore that ended early because of a cracked fingernail and blister.Keibert Ruiz hit a tiebreaking three-run homer in the eighth inning, Garrett homered twice for the first time in his career, and the Nationals beat the Boston Red Sox 6-2 on Wednesday night.“You always want to do well for your starting pitcher when he’s lights-out like that,” Garrett said. “Never felt like we were out of it or low-energy. We kept the energy going.”After Lane Thomas singled and Joey Meneses was hit by a pitch leading off the eighth, Ruiz drove an 0-1 changeup from Garrett Whitlock (5-4) to right-center to make it 5-2. Two pitches later, Garrett hit a no-doubt, 442-foot liner to center, his ninth of the season. Garrett also homered leading off the fourth.Gore allowed one hit while pitching into the seventh inning for Washington but departed with one out after throwing a first-p...

3 young teens arrested in random attack on man in Downtown Crossing

Published Sun, 23 Feb 2025 04:10:46 GMT

Three young teens appeared in court on criminal charges Tuesday in connection with the random beating of a man in Downtown Crossing on Monday night, officials said.Officers responding to a reported assault in progress in the area of 375 Washington St. around 8 p.m. found the man suffering from bruising to his left eye and lacerations near both eyelids and on his left hand, according to Suffolk District Attorney Kevin Hayden.The victim said he was walking on Washington Street when he made eye contact with one of the juveniles, who was him, ‘Why are you (expletive) staring at me?”When the man ran, he said a large group ran behind him and attacked him when he fell.A 14-year-old boy was charged with assault and battery with a dangerous weapon (shod foot), assault and battery, and assault and battery on a police officer. A second juvenile, a 15-year-old boy, was charged with assault and battery with a dangerous weapon (shod foot).Prosecutors delayed charging the third juvenil...

23 Audi Q5 is more than an option

Published Sun, 23 Feb 2025 04:10:46 GMT

Wrapped in District Green Metallic, the Audi Q5 is a very nice overall vehicle. Appealing to the consumer eye and priced right for the moderate buyer, the Audi Q5 is very practical.While riding higher in the Q5 SUV, Audi does a great job of ensuring the vehicle rides smoothly similar to that of a sedan, but for other Q-series SUV’s that is not necessarily the case as more sporty models tend to be stiffer. But for the Q5, a well-versed mid-size SUV with good sight lines and a smooth ride, is perfect for many consumers in today’s market. As Volkswagen, the parent company to Audi, develops similar sized SUVs in their fleet, we recognize some large differences amongst the brands.With 261 horsepower our Q5 S-line came with a 2.0 liter 4-cylinder engine and 273 lb-ft of torque. Paired with a 7-speed transmission, the 2023 Audi D5 S-Line was quiet with limited road noise and peppy at just the step of the pedal. While a typical Audi interior was present, our S-Line came with a P...

Battenfeld: Televising Trump’s trial will be the Super Bowl of politics

Published Sun, 23 Feb 2025 04:10:46 GMT

Democrats and Georgia prosecutors will try to humiliate Donald Trump in a televised courtroom appearance and trial, but the tactic could backfire if the former president succeeds in putting the politically-tainted judicial system on trial.Trump’s first appearance in court to face his charges, which will come sometime before Aug. 25, could be the Super Bowl of politics, drawing hundreds of millions of viewers around the world.It will be the first time live cameras have been permitted in Trump’s long legal saga.Prosecutors and the judge want the optic of treating Trump like any other criminal, complete with mug shots and showing up at the jailhouse.There are obvious disadvantages to Trump fighting his case live on TV.Every minute he has to spend in court is a minute he can’t be out there campaigning.Every dollar he spends defending himself, will be money he can’t spend on the campaign.Whether they stop him running for president they’ve already tried tying his hands behind his back and...

Patriots extra points: Robert Kraft denied Hall of Fame entry again, when will he get in?

Published Sun, 23 Feb 2025 04:10:46 GMT

GREEN BAY, Wis. — Patriots owner Robert Kraft was passed over for nomination into the Pro Football Hall of Fame on Wednesday, when the Coach/Contributor committee instead selected ex-Steelers and Lions coach Buddy Parker as its annual nominee.Kraft must wait another year to be inducted, which selection by the Coach/Contributor committee itself does not guarantee. Parker, like previous Coach/Contributor nominees before him, will only be inducted if he’s voted in by the Hall’s Selection Committee. Only one Coach/Contributor can be added to a Hall of Fame class each year.Related ArticlesNew England Patriots | Patriots-Packers joint practices Day 1: Ezekiel Elliott debuts, offense hobbled by 13 sacks in Green Bay New England Patriots | How Patriots’ Ezekiel Elliott can earn max value of one-year contract New England Patriots | Patriots left tackle Trent Brown feeling ‘great’ in return to practice field N...

One of Libya’s rival prime ministers warns militias against further clashes after 45 die

Published Sun, 23 Feb 2025 04:10:46 GMT

CAIRO (AP) — One of Libya’s rival prime ministers warned Thursday that his government would not tolerate any further militia fighting, days after the year’s bloodiest bout of clashes rocked the capital, Tripoli, killing at least 45 people.Violence ensued late on Monday between militiamen from the 444 brigade and its rival the Special Deterrence Force after Mahmoud Hamza, a senior commander of the brigade was held by the rival group at an airport in Tripoli, according to local media.The warning from Abdul Hamid Dbeibah — who heads the Tripoli-based government — came as Hamza was released and returned to his militia’s headquarters, according to footage aired by Libyan media late Wednesday.“We are used to the sound of clashes, but (coming near) civilians is forbidden,” said Dbeibah in a televised speech accompanied by tribal elders from eastern Tripoli, a district where both militias have a strong presence.During his 45-minute speech, the Tripoli-based prime minister also threatened to...

More than 30 stolen vehicles recovered, 3 arrested as police bust GTA car theft ring

Published Sun, 23 Feb 2025 04:10:46 GMT

Three men are facing more than 80 charges after police busted a multi-million dollar car theft ring in York Region, recovering dozens of stolen vehicles in the process.Investigators with York Regional Police, in conjunction with Peel Regional Police and the Ontario Provincial Police (OPP), began an investigation back in May 2023 and were able to identify three suspects.While executing eight search warrants, officers recovered 31 stolen vehicles valued at $2.8 million. Police also seized $30,000 in cash, police scanner devices, key re-programmers and more than 100 master keys.The trio of suspects are facing 83 charges including motor vehicle theft. The accused have been identified as:Ranvir Saggi, 24, of Richmond HillJasman Pannu, 21, of BramptonKuljeet Singh Sivia, 23, of Richmond Hill One of the suspects was out on bail for charges related to vehicle theft at the time of there arrest, according to police.The investigation is ongoing. Anyone with additional information is being...